Publications (Updated 5/2019):

Search for Dr. Ashley’s publications using Pubmed

Runyan CL, McIntosh SZ, Maestas MM, Quinn KE, Boren BP, Ashley RL. CXCR4 signaling at the ovine fetal-maternal interface regulates vascularization, CD34 + cell presence, and autophagy in the endometrium.  Biol Reprod. 2019 Jul 1;101(1):102-111. doi: 10.1093/biolre/ioz073.

DeAtley KL, Colgrave ML, Cánovas A, Wijffels G, Ashley RL, Silver GA, Rincon G, Medrano JF, Islas-Trejo A, Fortes MRS, Reverter A, Porto-Neto L, Lehnert SA, Thomas MG. Neuropeptidome of the Hypothalamus and Pituitary Gland of Indicine × Taurine Heifers: Evidence of Differential Neuropeptide Processing in the Pituitary Gland before and after Puberty. J Proteome Res. 2018 May 4;17(5):1852-1865. doi: 10.1021/acs.jproteome.7b00875. Epub 2018 Apr 6. PMID: 29510626

Young CH, Rothfuss HM, Gard PF, Muth A, Thompson PR, Ashley RL, Cherrington BD. Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells. Reproduction. 2017 Jan;153(1):1-10. doi: 10.1530/REP-16-0494. Epub 2016 Oct 10. PMID: 29565015 Free PMC Article

Sanchez NS, Quinn KE, Ashley AK, Ashley RL. In the ovine pituitary, CXCR4 is localized in gonadotropes and somatotropes and increases with elevated serum progesterone. Domest Anim Endocrinol. 2018 Jan;62:88-97. doi: 10.1016/j.domaniend.2017.10.003. Epub 2017 Oct 28.

Quinn KE, Prosser SZ, Kane KK, Ashley RL. Inhibition of chemokine (C-X-C motif) receptor four (CXCR4) at the fetal-maternal interface during early gestation in sheep: alterations in expression of chemokines, angiogenic factors and their receptors. J Anim Sci. 2017 Mar;95(3):1144-11153. doi: 10.2527/jas.2016.1271.PMID: 28380526

Salazar M, Lerma-Ortiz A, Hooks GM, Ashley AK, Ashley RL. Progestin-mediated activation of MAPK and AKT in nuclear progesterone receptor negative breast epithelial cells: The role of membrane progesterone receptors. Gene. 2016;591(1):6-13. doi: 10.1016/j.gene.2016.06.044. PubMed PMID: 27349565; PMCID: PMC4992424.

Quinn KE, Reynolds LP, Grazul-Bilska AT, Borowicz PP, Ashley RL. Placental development during early pregnancy: Effects of embryo origin on expression of chemokine ligand twelve (CXCL12). Placenta. 2016 Jul;43:77-80. doi: 10.1016/j.placenta.2016.05.008. Epub 2016 May 18. PMID: 27324103

Bairagi S, Quinn KE, Crane AR, Ashley RL, Borowicz PP, Caton JS, Redden RR, Grazul-Bilska AT, Reynolds LP. Maternal environment and placental vascularization in small ruminants. Theriogenology. 2016 Jul 1;86(1):288-305. doi: 10.1016/j.theriogenology.2016.04.042. Epub 2016 Apr 21. Review. PMID: 27173956

Coleson MP*, Sanchez NS*, Ashley AK, Ross TT, R. L. Ashley . (2015) Human chorionic gonadotropin increases serum progesterone, number of corpora lutea and angiogenic factors in pregnant sheep. Reproduction. Jul;1501):43-52. doi: 10.1530/REP-14-0632. Epub 2015 Apr 10.

Romero, J.J., A.Q. Antoniazzi, T.M. Nett, R.L. Ashley, B.T. Webb, N.P. Smirnova, R.C. Bott, J.E. Bruemmer, F.W. Bazer, R.V. Anthony, and T.R. Hansen. 2015. Temporal release, paracrine and endocrine actions of ovine conceptus-derived interferon-tau during early pregnancy. Biology of Reproduction. Dec;93(6):146. PMID: 26559679.

Reynolds, L.P., J.S. Haring, M.L. Johnson, R.L. Ashley, D.A. Redmer, P.P. Borowicz, and A.T. Grazul-Bilska. 2015. Placental development during early pregnancy in sheep: estrogen and progesterone receptor messenger RNA expression in pregnancies derived from in vivo-produced and in vitro-produced embryos. Domestic Animal Endocrinology. Oct; 53:60-9. PMID: 26119037.

Henkes, L.E., J.K. Pru, R.L. Ashley, R.V. Anthony, D.N. Veeramachaneni, K.C. Gates, and T.R. Hansen. 2015. Embryo Mortality in Isg15-/- Mice Is Exacerbated by Environmental Stress. Biology of Reproduction. 92(2):36. PMID: 25505199.

Canovas, A. Reverter, A., DeAtley, K.L., Ashley, R.L., Colgrave, M.L., Fortes, M. R., Islas-Trejo, A., Lehnert, S., Porto-Neto, L., Rincon, G., Silver, G.A., Snelling, W.M., Medrano, J.F., Thomas, M.G. 2014. Multi-Tissue Omics Analyses Reveal Molecular Regulatory Networks for Puberty in Composite Beef Cattle. PLoS One. Jul 21;9(7):e102551. PMID: 25048735.

Quinn, K.E., A.K. Ashley, L.P. Reynolds, A.T. Grazul-Bilska, R.L. Ashley. 2014. Activation of the CXCL12/CXCR4 signaling axis may drive vascularization of the ovine placenta. Domestic Animal Endocrinology. 47:11-21.

Hansen, T.R., J.J. Romero, A.Q. Antoniazzi, R.C. Bott, R.L. Ashley, B.T. Webb, L.E. Henkes, N.P. Smirnova. 2013. Endocrine conceptus signaling in ruminants. Animal Reproduction. (3):311-321.

Antoniazzi, A.Q., B.T. Webb, J.J. Romero, R.L. Ashley, N.P. Smirnova, L.E. Henkes, R.C. Bott, J.F. Oliveira, G.D. Niswender, F.W. Bazer, and T.R. Hansen. 2013. Endocrine delivery of interferon-tau protects the corpus luteum from prostaglandin F2 alpha-induced luteolysis in ewes. Biology of Reproduction.

Ashley, R.L., A.Q. Antoniazzi, R.V. Anthony, and T.R. Hansen. 2011. The chemokine receptor CXCR4 and its ligand CXCL12 are activated during implantation and placentation in sheep. Reproductive Biology and Endocrinology. Nov 3; 9:148.

Hansen, T.R., L.E. Henkes, R.L. Ashley, R.C. Bott, A.Q. Antoniazzi, and H. Han. 2010. Endocrine actions of interferon-tau in ruminants. Reproduction in Domestic Ruminants. Vol 7. J Reprod Fertil: 1-22.

Ashley, R.L., L.E. Henkes, G.J. Bouma, J.K. Pru, and T.R. Hansen. 2010. Deletion of the Isg15 gene results in up-regulation of decidual cell survival genes and down-regulation of adhesion genes: Implication for regulation by interleukin-1 beta. Endocrinology. Sep, 151(9): 4527-36.

Arreguin-Arevalo J.A., Ashley R.L., Wagenmaker E.R., Oakley A.E., Karsch F.J., Nett T.M. 2010. Membrane-initiated actions of estradiol (E2) in the regulation of LH secretion in ovariectomized (OVX) ewes. Reproductive Biology and Endocrinology. 8(1):40 (10 May 2010).

Bott, R.C., R.L. Ashley, L.E. Henkes, A.Q. Antoniazzi, J.E. Bruemmer, G.D. Niswender, F.W. Bazer, T.E. Spencer, N.P. Smirnova, R.V. Anthony, and T.R. Hansen. 2010. Uterine vein infusion of interferon tau (IFNT) extends luteal lifespan in ewes. Biology of Reproduction. Apr;82(4):725-35.

Ashley, R.L., J.A. Arreguin-Arevalo, and T.M. Nett. 2009.  Binding characteristics of the ovine membrane progesterone receptor alpha and expression of the receptor during the estrous cycle. Reproductive Biology and Endocrinology. 7:42 (11 May 2009).

Oliveira, J.F., L.E. Henkes, R.L. Ashley, S.H. Purcell, N.P. Smirnova, R.V. Anthony, T.R. Hansen.  2008.  Expression of ISGs in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein.  Endocrinology.  Mar, 149(3):1252-9.

Ashley, R.L., C. M. Clay, T.A. Farmerie, G.D. Niswender, and T.M. Nett. 2006. Cloning and characterization of an ovine intracellular seven transmembrane receptor for progesterone that mediates calcium mobilization. Endocrinology. 147(9):4151-9.

Ashley, A.K., R.L. Ashley, M.A.Siepel, and J.R. Strickland. 2006. Toxicokinetic profile of swainsonine following acute and subacute exposure in sheep. New Zealand Journal of Veterinary Medicine. 54(1):34-40.